Significant intratumoral heterogeneity of human epidermal growth factor receptor 2 status in gastric cancer: A comparative study of immunohistochemistry, FISH , and dual‐color in situ hybridization
Author:
Affiliation:
1. Department of Oncologic Pathology Mie University Graduate School of Medicine TsuJapan
2. Department of Clinical Nutrition Suzuka University of Medical Science Suzuka Japan
Publisher
Wiley
Subject
Cancer Research,Oncology,General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/cas.12886
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3. Surgical specimen can be replaced by core samples in assessment of ER, PR and HER-2 for invasive breast cancer
4. Comparison of core needle biopsy (CNB) and surgical specimens for accurate preoperative evaluation of ER, PgR and HER2 status of breast cancer patients
5. Clinical importance of HER2 immunohistologic heterogeneous expression in core-needle biopsies vs resection specimens for equivocal (immunohistochemical score 2+) cases
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