Activation of protein C and thrombin activable fibrinolysis inhibitor on cultured human endothelial cells

Author:

Wu C.12,Kim P. Y.12ORCID,Swystun L. L.3,Liaw P. C.12,Weitz J. I.124

Affiliation:

1. Thrombosis and Atherosclerosis Research Institute; Hamilton ON Canada

2. Department of Medicine; McMaster University; Hamilton ON Canada

3. Department of Pathology and Molecular Medicine; Queen's University; Kingston ON Canada

4. Department of Biochemistry and Biomedical Sciences; McMaster University; Hamilton ON Canada

Funder

Canadian Institutes of Health Research

Heart and Stroke Foundation of Canada

Hamilton Health Sciences Early Career Award and New Investigator Fund

Publisher

Wiley

Subject

Hematology

Reference36 articles.

1. Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C;Esmon;J Biol Chem,1982

2. Initiation of the protein C pathway;Esmon;Ann N Y Acad Sci,1991

3. Structure-function relationships of the thrombin-thrombomodulin interaction;Sadler;Haemostasis,1993

4. Activation of thrombin-activable fibrinolysis inhibitor requires epidermal growth factor-like domain 3 of thrombomodulin and is inhibited competitively by protein C;Kokame;J Biol Chem,1998

5. Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C;Esmon;Proc Nat Acad Sci USA,1981

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