AAV‐mediated expression of secreted and transmembrane αKlotho isoforms rescues relevant aging hallmarks in senescent SAMP8 mice-Reference-Cited by-同舟云学术

AAV‐mediated expression of secreted and transmembrane αKlotho isoforms rescues relevant aging hallmarks in senescent SAMP8 mice

Published:2022-03-10 Issue:4 Volume:21 Page:
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Roig‐Soriano J.¹^ORCID,Griñán‐Ferré C.²^ORCID,Espinosa‐Parrilla J. F.¹^ORCID,Abraham C. R.³^ORCID,Bosch A.¹⁴⁵⁶^ORCID,Pallàs M.²^ORCID,Chillón Miguel¹⁴⁵⁷^ORCID

Affiliation:

1. Institut de Neurociènces (INc) Department of Biochemistry and Molecular Biology Universitat Autònoma Barcelona Bellaterra Spain

2. Pharmacology Section Department of Pharmacology, Toxicology, and Therapeutic Chemistry Faculty of Pharmacy and Food Sciences Institut de Neurosciències‐Universitat de Barcelona (NeuroUB) Barcelona Spain

3. Department of Pharmacology and Experimental Therapeutics Boston University School of Medicine Boston Massachusetts USA

4. Vall d'Hebron Institut de Recerca (VHIR) Barcelona Spain

5. Unitat producció de Vectors (UPV) Universitat Autònoma Barcelona Bellaterra Spain

6. Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED) Instituto de Salud Carlos III Madrid Spain

7. Institució Catalana de Recerca i Estudis Avançats (ICREA) Passeig Lluis Companys Barcelona Spain

Funder

Generalitat de Catalunya

Publisher

Wiley

Subject

Cell Biology,Aging

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.13581

Reference46 articles.

1. Klotho Is a Neuroprotective and Cognition-Enhancing Protein

2. SAMP8 mice as a neuropathological model of accelerated brain aging and dementia: Toshio Takeda's legacy and future directions

3. Bone strength and its determinants

4. Tests for emotionality in rats and mice: A review

5. Association of human aging with a functional variant of klotho

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