Eosinophilic allergic rhinitis is strongly associated with the <scp>CD45RB<sup>lo</sup></scp> subset of <scp>CD161</scp><sup>+</sup> Th2 cells that secretes <scp>IL</scp>‐2, <scp>IL</scp>‐3, <scp>IL</scp>‐4, <scp>IL</scp>‐5, <scp>IL</scp>‐9, and <scp>IL</scp>‐13-Reference-Cited by-同舟云学术

Eosinophilic allergic rhinitis is strongly associated with the CD45RB^lo subset of CD161⁺ Th2 cells that secretes IL‐2, IL‐3, IL‐4, IL‐5, IL‐9, and IL‐13

Published:2023-08-07 Issue:10 Volume:78 Page:2794-2798
ISSN:0105-4538
Container-title:Allergy
language:en
Short-container-title:Allergy

Author:

Lee Wendy W. L.¹,Puan Kia Joo¹²,Lee Bernett¹³,Chua Celine¹,Koh Ser Mei¹,Yusof Nurhashikin¹,Tan Kim Peng¹,Luis Boris San¹⁴,Ong Jocelyn¹,Merid Simon Kebede⁵,Ang Rachel¹,Chan Xue Ying¹,Hui Low Jing¹,Terenzani Elisa¹^ORCID,Lum Josephine¹,Foo Shihui¹,Zolezzi Francesca¹,Yan Annabelle Tay Sok⁶⁷,Melen Erik⁵⁸,Yi Soh Jian⁹,Rotzschke Olaf¹,Andiappan Anand Kumar¹^ORCID

Affiliation:

1. Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR) Singapore Singapore

2. Shanghai Junshi Biosciences Co Ltd Shanghai China

3. Centre for Biomedical Informatics Nanyang Technological University Singapore Singapore

4. Institute of Molecular and Cell Biology (IMCB) A*STAR, Proteos Singapore Singapore

5. Department of Clinical Science and Education Södersjukhuset Karolinska Institutet Stockholm Sweden

6. Department of Otolaryngology National University Hospital Singapore Singapore

7. Department of Otolaryngology, Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore

8. Department of Paediatrics Sachs' Children's Hospital Stockholm Sweden

9. Department of Paediatrics National University Hospital Singapore Singapore

Funder

Agency for Science, Technology and Research

National Research Foundation

Biomedical Research Council

European Academy of Allergy and Clinical Immunology

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/all.15846

Reference6 articles.

1. Allergies to food and airborne allergens in children and adolescents: role of epigenetics in a changing environment

2. Allergic airway diseases in a tropical urban environment are driven by dominant mono‐specific sensitization against house dust mites

3. CRTH2, an orphan receptor of T-helper-2-cells, is expressed on basophils and eosinophils and responds to mast cell-derived factor(s)

4. Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human TH2 cell subpopulation with enhanced function

5. A phenotypically and functionally distinct human T H 2 cell subpopulation is associated with allergic disorders

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