KH‐17, a simplified derivative of bongkrekic acid, weakly inhibits the mitochondrial ADP/ATP carrier from both sides of the inner mitochondrial membrane-Reference-Cited by-同舟云学术

KH‐17, a simplified derivative of bongkrekic acid, weakly inhibits the mitochondrial ADP/ATP carrier from both sides of the inner mitochondrial membrane

Published:2023-01 Issue:4 Volume:101 Page:865-872
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Takegawa Kazuto¹²,Ito Takeshi¹²^ORCID,Yamamoto Atsushi³,Yamazaki Naoshi²,Shindo Mitsuru⁴,Shinohara Yasuo¹²^ORCID

Affiliation:

1. Institute for Genome Research, Institute of Advanced Medical Sciences Tokushima University Tokushima Japan

2. Graduate School of Pharmaceutical Sciences Tokushima University Tokushima Japan

3. Faculty of Pharmaceutical Sciences Suzuka University of Medical Science Suzuka Japan

4. Institute for Materials Chemistry and Engineering Kyushu University Kasuga Japan

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cbdd.14194

Reference22 articles.

1. Mitochondrial ADP/ATP Carrier: Preventing Conformational Changes by Point Mutations Inactivates Nucleotide Transport Activity

2. Synthesis and evaluation of simplified functionalized bongkrekic acid analogs

3. Suramin Inhibits Mitochondrial ADP/ATP Carrier, Not Only from the Cytosolic Side But Also from the Matrix Side, of the Mitochondrial Inner Membrane

4. Characterization of drug-induced human mitochondrial ADP/ATP carrier inhibition

5. The effect of adenine nucleotides and pH on the inhibition of oxidative phosphorylation by bongkrekic acid

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