Molecular mechanism of positive allosteric modulation of the metabotropic glutamate receptor 2 by JNJ-46281222-Reference-Cited by-同舟云学术

Molecular mechanism of positive allosteric modulation of the metabotropic glutamate receptor 2 by JNJ-46281222

Published:2016-01-13 Issue:3 Volume:173 Page:588-600
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:British Journal of Pharmacology

Author:

Doornbos Maarten L J¹,Pérez-Benito Laura²³,Tresadern Gary²,Mulder-Krieger Thea¹,Biesmans Ilse⁴,Trabanco Andrés A²,Cid Jose María²,Lavreysen Hilde⁴,IJzerman Adriaan P¹,Heitman Laura H¹

Affiliation:

1. Division of Medicinal Chemistry, Leiden Academic Centre for Drug Research (LACDR); Leiden University; Leiden The Netherlands

2. Janssen Research and Development; Toledo Spain

3. Laboratori de Medicina Computacional Unitat de Bioestadistica, Facultat de Medicina; Universitat Autonoma de Barcelona; Bellaterra Spain

4. Janssen Research and Development; Beerse Belgium

Publisher

Wiley

Subject

Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bph.13390/fullpdf

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4. Characterization of [3H]-(2S,2′R,3′R)-2-(2′,3′-dicarboxy-cyclopropyl)glycine ([3H]-DCG IV) binding to metabotropic mGlu2 receptor-transfected cell membranes;Cartmell;Br. J. Pharmacol.,1998

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