Importance of functional groups in predicting the activity of small molecule inhibitors for Bcl-2 and Bcl-xL-Reference-Cited by-同舟云学术

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Importance of functional groups in predicting the activity of small molecule inhibitors for Bcl-2 and Bcl-xL

Published:2017-03-01 Issue:2 Volume:90 Page:308-316
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Kanakaveti Vishnupriya¹^ORCID,Sakthivel Ramasamy¹,Rayala S. K.²,Gromiha M. Michael¹

Affiliation:

1. Protein Bioinformatics Lab; Department of Biotechnology; Bhupat and Jyoti Mehta School of Biosciences; Indian Institute of Technology Madras; Chennai Tamil Nadu India

2. Molecular Oncology Lab; Department of Biotechnology; Bhupat and Jyoti Mehta School of Biosciences; Indian Institute of Technology Madras; Chennai Tamil Nadu India

Funder

Department of Biotechnology, Government of India

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12952/fullpdf

Reference32 articles.

1. Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

2. Hallmarks of Cancer: The Next Generation

3. Involvement of the bcl -2 Gene in Human Follicular Lymphoma

4. The Bcl-2 apoptotic switch in cancer development and therapy

5. The BCL-2 protein family: opposing activities that mediate cell death

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4. Exploring the chemical space of protein–protein interaction inhibitors through machine learning;Scientific Reports;2021-06-28

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