Biological screening of cucurbitacin inspired estrone analogs targeting mitogen-activated protein kinase (MAPK) pathway-Reference-Cited by-同舟云学术

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Biological screening of cucurbitacin inspired estrone analogs targeting mitogen-activated protein kinase (MAPK) pathway

Published:2017-04-25 Issue:3 Volume:90 Page:478-484
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Ahmed Mahmoud S.¹^ORCID,El-Senduny Fardous²,Taylor Jessica³,Halaweish Fathi T.³

Affiliation:

1. Department of Pharmaceutical Chemistry; Faculty of Pharmacy; The British University in Egypt; El-Sherouk Cairo Egypt

2. Department of Chemistry; Faculty of Science; Mansoura University; Mansoura Egypt

3. Department of Chemistry and Biochemistry; South Dakota State University; Brookings SD USA

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12963/fullpdf

Reference21 articles.

1. Cucurbitacin B inhibits STAT3 and the Raf/MEK/ERK pathway in leukemia cell line K562

2. Biological activities and potential molecular targets of cucurbitacins

3. Cucurbitacins fromTrichosanthes kirilowiias the Inhibitory Components on Tyrosinase Activity and Melanin Synthesis of B16/F10 Melanoma Cells

4. Cucurbitacin covalent bonding to cysteine thiols: the filamentous-actin severing protein Cofilin1 as an exemplary target

5. Cucurbitacins: potential candidates targeting mitogen-activated protein kinase pathway for treatment of melanoma

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1. Synthesis and biological activity of 11-Oxygenated and heterocyclic estrone analogs in pancreatic cancer monolayers and 3D spheroids;Bioorganic & Medicinal Chemistry;2024-04

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3. Development of pyrolo[2,3-c]pyrazole, pyrolo[2,3-d]pyrimidine and their bioisosteres as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological evaluation and molecular dynamics investigations;Bioorganic Chemistry;2023-10

4. Deacetylated Sialic Acid Sensitizes Lung and Colon Cancers to Novel Cucurbitacin-Inspired Estrone Epidermal Growth Factor Receptor (EGFR) Inhibitor Analogs;Molecules;2023-08-26

5. Antiproliferation and apoptosis studies of estrone pharmacophores in triple‐negative breast cancer;Chemical Biology & Drug Design;2023-07-27

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