Osteocytes and mechanical loading: The Wnt connection
Author:
Affiliation:
1. Department of Anatomy & Cell BiologyIndiana University School of Medicine Indianapolis Indiana
Publisher
Wiley
Subject
Otorhinolaryngology,Oral Surgery,Surgery,Orthodontics
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1111/ocr.12282
Reference22 articles.
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2. Six novel missense mutations in the LDL receptor‐related protein 5 (LRP5) gene in different conditions with an increased bone density;Van Wesenbeeck L;Am J Hum Genet,2003
3. A mutation in the LDL receptor‐related protein 5 gene results in the autosomal dominant high‐bone‐mass trait;Little RD;Am J Hum Genet,2002
4. The Wnt co‐receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment;Sawakami K;J Biol Chem,2006
5. Analysis of multiple bone responses to graded strains above functional levels, and to disuse, in mice in vivo show that the human Lrp5 G171V High Bone Mass mutation increases the osteogenic response to loading but that lack of Lrp5 activity reduces it;Saxon LK;Bone,2011
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