Netazepide, a gastrin/CCK2receptor antagonist, causes dose-dependent, persistent inhibition of the responses to pentagastrin in healthy subjects
Author:
Affiliation:
1. Hammersmith Medicines Research; Central Middlesex Hospital; London NW10 7NS UK
2. James Black Foundation; Half Moon Lane Dulwich London SE24 9JE UK
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12099/fullpdf
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2. YF476 is a new potent and selective gastrin/cholecystokinin-B receptor antagonist in vitro and in vivo;Takinami;Aliment Pharmacol Ther,1997
3. Effects of YF476, a potent and selective gastrin/CCK-B receptor antagonist, on gastric acid secretion in beagle dogs with gastric fistula;Takemoto;Arzneim Forsch,1998
4. Guide to receptors and channels (GRAC);Alexander;Br J Pharmacol,2011
5. Single oral doses of netazepide (YF476), a gastrin receptor antagonist, cause dose-dependent, sustained increases in 24-h gastric pH compared with placebo and ranitidine in healthy subjects;Boyce;Aliment Pharmacol Ther,2012
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