(3R)-N-(1-(tert-Butylcarbonylmethyl)-2,3-dihydro-2-oxo-5-(2-pyridyl)-1H- 1,4-benzodiazepin-3-yl)-N‘-(3-(methylamino)phenyl)urea (YF476): A Potent and Orally Active Gastrin/CCK-B Antagonist-Reference-Cited by-同舟云学术

(3R)-N-(1-(tert-Butylcarbonylmethyl)-2,3-dihydro-2-oxo-5-(2-pyridyl)-1H- 1,4-benzodiazepin-3-yl)-N‘-(3-(methylamino)phenyl)urea (YF476): A Potent and Orally Active Gastrin/CCK-B Antagonist

Published:1997-01-01 Issue:3 Volume:40 Page:331-341
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Semple Graeme¹,Ryder Hamish¹,Rooker David P.¹,Batt Andrzej R.¹,Kendrick David A.¹,Szelke Michael¹,Ohta Mitsuaki¹,Satoh Masato¹,Nishida Akito¹,Akuzawa Shinobu¹,Miyata Keiji¹

Affiliation:

1. Ferring Research Institute, Chilworth Research Centre, Chilworth, Southampton SO16 7NP, U.K., and Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co., Ltd., 21, Miyukigaoka, Tsukuba, Ibaraki 305, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm960669%2B

Reference35 articles.

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2. Effect of omeprazole--a gastric proton pump inhibitor--on pentagastrin stimulated acid secretion in man.

3. The relationship between gastric acid secretion and gastric H+,K+-ATPase activity.

4. Gastric ECL-Cell Hyperplasia and Carcinoids in Rodents Following Chronic Administration of H2-Antagonists SK&F 93479 and Oxmetidine and Omeprazole

5. The Syndrome of Gastric Argyrophil Carcinoid Tumors and Nonantral Gastric Atrophy

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