Cross-sectional study of Treponema pallidum PCR in diagnosis of primary and secondary syphilis

Author:

Costa-Silva Miguel1,Coutinho Daniel2,Sobrinho-Simões Joana3,Azevedo Filomena1,Lisboa Carmen14

Affiliation:

1. Dermatovenereology Department; Centro Hospitalar de São João; EPE; Porto Portugal

2. Infectious Diseases Department; Centro Hospitalar do Baixo Vouga; EPE; Aveiro Portugal

3. Clinical Pathology Department; Centro Hospitalar de S.João; EPE; Porto Portugal

4. Microbiology Department; Faculty of Medicine; University of Porto; Porto Portugal

Publisher

Wiley

Subject

Dermatology

Reference12 articles.

1. Charles B Pathophysiology, transmission and natural history of syphilis. Literature review current through http://www.uptodate.com/contents/syphilis-epidemiology-pathophysiology-and-clinical-manifestations-in-hiv-uninfected-patients

2. European Centre for Disease Prevention and Control (ECDC) Annual Epidemiological Report 2014 - Sexually Transmitted Infection Including HIV and Blood-Born Viroses Stockholm http://ecdc.europa.eu/en/publications/Publications/sexually-transmited-infections-HIV-AIDS-blood-borne-annual-epi-report-2014.pdf

3. Sensitivity, specificity and likelihood ratios of PCR in the diagnosis of syphilis: a systematic review and meta-analysis;Gayet-Ageron;Sex Transm Infect,2013

4. European Centre for Disease Prevention and Control STD Surveillance Case Definitions http://www.ecdc.europa.eu/en/activities/surveillance/sti/Pages/Case%20definition.aspx

5. Development of a real-time PCR assay to detect Treponema pallidum in clinical specimens and assessment of the assay's performance by comparison with serological testing;Leslie;J Clin Microbiol,2007

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