Positive effect of <i>Limosilactobacillus plantarum</i> grx16 on nonalcoholic fatty liver disease in rats-Reference-Cited by-同舟云学术

Positive effect of Limosilactobacillus plantarum grx16 on nonalcoholic fatty liver disease in rats

Published:2023-04-27 Issue:3 Volume:76 Page:710-716
ISSN:1364-727X
Container-title:International Journal of Dairy Technology
language:en
Short-container-title:Int J of Dairy Tech

Author:

Qu Hengxian¹²^ORCID,Zhang Longfei¹²,Liu Xiaoxiao¹²,Liu Yang¹²,Mao Kaidong³,Shen Guiqi³,Wa Yunchao¹²,Chen Dawei¹²,Huang Yujun¹²,Chen Xia¹²,Gu Ruixia¹²

Affiliation:

1. College of Food Science and Technology Yangzhou University Yangzhou Jiangsu 225000 China

2. Key Lab of Dairy Biotechnology and Safety Control Yangzhou Jiangsu 225000 China

3. Shanghai HOWYOU Biotechnology Co., Ltd. Shanghai 200000 China

Abstract

We aimed to investigate the potential and mechanism of probiotics as digestive enzyme inhibitors to alleviate nonalcoholic fatty liver disease (NAFLD). We compared the level of NAFLD in rats before and after Limosilactobacillus plantarum grx16 intervention, as well as changes in gut digestive enzymes and inflammatory factors. L. plantarum grx16 inhibited the absorption of starch and triglycerides by inhibiting the activity of gut amylase and lipase to alleviate insulin resistance and reduce lipid accumulation in the body, thereby alleviating the inflammatory response, and thus alleviating NAFLD in rats.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Yangzhou University

Publisher

Wiley

Subject

Process Chemistry and Technology,Bioengineering,Food Science

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/1471-0307.12956

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