Experimental and Computational Study of the Interaction of Novel Colchicinoids with a Recombinant Human αI/βI-Tubulin Heterodimer-Reference-Cited by-同舟云学术

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Experimental and Computational Study of the Interaction of Novel Colchicinoids with a Recombinant Human αI/βI-Tubulin Heterodimer

Published:2013-06-21 Issue:1 Volume:82 Page:60-70
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Mane Jonathan Y.¹,Semenchenko Valentyna²,Perez-Pineiro Rolando²,Winter Philip¹,Wishart David,Tuszynski Jack A.

Affiliation:

1. Department of Oncology; University of Alberta; Edmonton; AB; Canada; T6G 1Z2

2. Department of Biological Sciences; University of Alberta; Edmonton; AB; Canada; T6G 2E9

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12132/fullpdf

Reference59 articles.

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2. Promotion of microtubule assembly in vitro by taxol;Schiff;Nature,1979

3. Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action;Bollag;Cancer Res,1995

4. Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach;Canales;ACS Chem Biol,2011

5. Peloruside A synergizes with other microtubule stabilizing agents in cultured cancer cell lines;Wilmes;Mol Pharm,2007

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1. Computational Approaches to the Rational Design of Tubulin-Targeting Agents;Biomolecules;2023-02-02

2. Novel colchicine derivative CR42-24 demonstrates potent anti-tumor activity in urothelial carcinoma;Cancer Letters;2022-02

3. RM1 Semiempirical Model: Chemistry, Pharmaceutical Research, Molecular Biology and Materials Science;Journal of the Brazilian Chemical Society;2018

4. Mobility and Core-Protein Binding Patterns of Disordered C-Terminal Tails in β-Tubulin Isotypes;Biochemistry;2017-03-17

5. Tools for the rational design of bivalent microtubule-targeting drugs;Biochemical and Biophysical Research Communications;2016-10

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