Insights into the Interaction of Discodermolide and Docetaxel with Tubulin. Mapping the Binding Sites of Microtubule-Stabilizing Agents by Using an Integrated NMR and Computational Approach-Reference-Cited by-同舟云学术

Insights into the Interaction of Discodermolide and Docetaxel with Tubulin. Mapping the Binding Sites of Microtubule-Stabilizing Agents by Using an Integrated NMR and Computational Approach

Published:2011-05-13 Issue:8 Volume:6 Page:789-799
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Canales Angeles¹²,Rodríguez-Salarichs Javier¹³,Trigili Chiara¹,Nieto Lidia¹,Coderch Claire⁴,Andreu José Manuel¹,Paterson Ian⁵,Jiménez-Barbero Jesús¹,Díaz J. Fernando¹

Affiliation:

1. Dept. Chemical and Physical Biology, Centro de Investigaciones Biológicas, Consejo Superior de Investigaciones Científicas, Ramiro de Maeztu 9, 28040 Madrid, Spain

2. Departamento de Química Orgánica I. Facultad de Ciencias Químicas, Universidad Complutense de Madrid, Avda Complutense s/n, 28040 Madrid, Spain

3. Centro de Estudios Avanzados de Cuba, Carretera San Antonio km 1 1/2, Valle Grande, La Lisa, Ciudad Habana, CP 17100, Cuba

4. Departamento de Farmacología, Universidad de Alcalá, E-28871 Alcalá de Henares, Madrid, Spain

5. University Chemical Laboratory, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb200099u

Reference50 articles.

1. Anticancer Agents from Natural Products

2. The Renaissance of Natural Products as Drug Candidates

3. Impact of Natural Products on Developing New Anti-Cancer Agents

4. Microtubule Interactions with Chemically Diverse Stabilizing Agents: Thermodynamics of Binding to the Paclitaxel Site Predicts Cytotoxicity

5. Macromolecular Accessibility of Fluorescent Taxoids Bound at a Paclitaxel Binding Site in the Microtubule Surface

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