“Protein aggregates” contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation-Reference-Cited by-同舟云学术

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“Protein aggregates” contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation

Published:2021-03-31 Issue:5 Volume:20 Page:
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Shmookler Reis Robert J.¹²³^ORCID,Atluri Ramani²,Balasubramaniam Meenakshisundaram²,Johnson Jay³,Ganne Akshatha³,Ayyadevara Srinivas¹²

Affiliation:

1. Central Arkansas Veterans Healthcare System Little Rock AR USA

2. Department of Geriatrics University of Arkansas for Medical Sciences Little Rock AR USA

3. BioInformatics Program University of Arkansas for Medical Sciences and University of Arkansas at Little Rock Little Rock AR USA

Funder

U.S. Department of Veterans Affairs

National Institute on Aging

Publisher

Wiley

Subject

Cell Biology,Ageing

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.13326

Reference72 articles.

1. Protein synthesis and quality control in aging

2. Proteins in aggregates functionally impact multiple neurodegenerative disease models by forming proteasome‐blocking complexes

3. PIP3-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans

4. Aspirin-Mediated Acetylation Protects Against Multiple Neurodegenerative Pathologies by Impeding Protein Aggregation

5. Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls

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2. Cell redistribution of G quadruplex‐structured DNA is associated with morphological changes of nuclei and nucleoli in neurons during tau pathology progression;Brain Pathology;2024-04-22

3. Protein G-quadruplex interactions and their effects on phase transitions and protein aggregation;Nucleic Acids Research;2024-04-04

4. The Role of Tau Pathology in Alzheimer’s Disease and Down Syndrome;Journal of Clinical Medicine;2024-02-27

5. Analyzing the implications of protein folding delay caused by translation;2024-01-27

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