Optimum designs for non-linear mixed effects models in the presence of covariates

Author:

Bogacka Barbara1,Latif Mahbub A. H. M.23,Gilmour Steven G.4,Youdim Kuresh5

Affiliation:

1. School of Mathematical Sciences, Queen Mary; University of London; London E1 4NS UK

2. Institute of Statistical Research and Training; University of Dhaka; Dhaka-1000 Bangladesh

3. Center for Clinical Epidemiology; St Luke's International University; 3-6-2 Tsukiji Chuo-ku Tokyo 104-0045 Japan

4. Department of Mathematics; King's College London; Strand London WC2R 2LS UK

5. Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel; F. Hoffmann-La Roche Ltd; Grenzacherstrasse 124 4070 Basel Switzerland

Publisher

Wiley

Subject

Applied Mathematics,General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine,Statistics and Probability

Reference17 articles.

1. Designing for a response transformation parameter;Atkinson;Journal of the Royal Statistical Society (B),1997

2. Relative curvature measures of nonlinearity;Bates;Journal of the Royal Statistical Society (B),1980

3. A population approach to enzyme characterization and identification: Application to Phenacetin O-Deethylation;Belle;Pharmaceutical Research,2000

4. Comparison of two design optimality criteria applied to a nonlinear model;Bogacka;Journal of Biopharmaceutical Statistics,2004

5. IVGTT glucose minimal model covariate selection by nonlinear mixed-effects approach;Denti;American Journal of Physiological Endocrinol Metabolism,2010

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