Synthesis, Antifolate and Anticancer Activities ofN5-Substituted 8,10-Dideazatetrahydrofolate Analogues-Reference-Cited by-同舟云学术

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Synthesis, Antifolate and Anticancer Activities ofN5-Substituted 8,10-Dideazatetrahydrofolate Analogues

Published:2015-12-29 Issue:3 Volume:87 Page:444-454
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Tian Chao¹,Zhang Zhili¹,Zhou Shouxin¹,Yuan Mengmeng¹,Wang Xiaowei¹,Liu Junyi¹²

Affiliation:

1. Department of Chemical Biology; School of Pharmaceutical Sciences; Peking University; Beijing 100191 China

2. State Key Laboratory of Natural and Biomimetic Drugs; Peking University; Beijing 100191 China

Funder

National Natural Science Foundation of China

Ministry of Science and Technology of China

Peking University Health Science Center

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12681/fullpdf

Reference23 articles.

1. The renewed potential for folate antagonists in contemporary cancer chemotherapy;Berman;J Med Chem,1991

2. Anticancer antifolates: current status and future directions;McGuire;Curr Pharmacol Des,2003

3. Antimicrobial dihydrofolate reductase inhibitors-achievements and future options: review;Then;J Chemother,2004

4. Mechanisms of resistance of malaria parasites to antifolates;Gregson;Pharmacol Rev,2005

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4. Design, synthesis and biological activity of N-substituted tetrahydropteroate analogs as non-classical antifolates against cobalamin-dependent methionine synthase and potential anticancer agents;European Journal of Medicinal Chemistry;2020-03

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