Time to optimize vaccination strategies in blood cancer patients

Author:

Muhsen Ibrahim N.1ORCID,Heslop Helen E.12ORCID

Affiliation:

1. Dan L. Duncan Comprehensive Cancer Center Baylor College of Medicine Houston Texas USA

2. Center for Cell and Gene Therapy, Baylor College of Medicine Texas Children's Hospital, Houston Methodist Hospital Houston Texas USA

Abstract

Immune response to vaccinations is dampened in patients with indolent lymphomas due to disease and treatment‐related factors. The study by Lim et al. demonstrated impaired humoral response but intact cellular response to the SARS‐CoV2 vaccine in patients with follicular lymphoma receiving front‐line therapy. The results highlight the importance of several factors in predicting immune response to vaccination and provide estimates of immune response for different clinical scenarios and treatment points.Commentary on: Lim et al. Immunogenicity of COVID‐19 vaccines in patients with follicular lymphoma receiving frontline chemoimmunotherapy. Br J Haematol 2024;205:440‐451.

Publisher

Wiley

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