T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study

Author:

Angyal Adrienn,Longet Stephanie,Moore Shona C,Payne Rebecca P,Harding Adam,Tipton Tom,Rongkard Patpong,Ali Mohammad,Hering Luisa M,Meardon Naomi,Austin James,Brown Rebecca,Skelly Donal,Gillson Natalie,Dobson Sue L,Cross Andrew,Sandhar Gurjinder,Kilby Jonathan A,Tyerman Jessica K,Nicols Alexander R,Spegarova Jarmila S,Mehta Hema,Hornsby Hailey,Whitham Rachel,Conlon Christopher P,Jeffery Katie,Goulder Philip,Frater John,Dold Christina,Pace Matthew,Ogbe Ane,Brown Helen,Ansari M Azim,Adland Emily,Brown Anthony,Chand Meera,Shields Adrian,Matthews Philippa C,Hopkins Susan,Hall Victoria,James William,Rowland-Jones Sarah L,Klenerman Paul,Dunachie Susanna,Richter Alex,Duncan Christopher J A,Barnes Eleanor,Carroll Miles,Turtle Lance,de Silva Thushan I,Harding Adam,Watson Adam,Shields Adrian,Angyal Adrienn,Alhussni Ahmed,Richter Alex,Nicols Alexander,Deeks Alexandra,Webb-Bridges Alice,Cross Andrew,Ogbe Ane,Jämsén Anni,Brown Anthony,Chawla Anu,Dold Christina,Duncan Christopher,Conlon Christopher,Skelly Donal,O'Donnell Denise,Barnes Eleanor,Adland Emily,Weeks Esme,Sandhar Gurjinder,Hornsby Hailey,Brown Helen,Mehta Hema,Abuelgasim Hibatullah,Xiao Huiyuan,Austin James,Spegarova Jarmila,Holmes Jennifer,Haworth Jenny,Tyerman Jessica,Frater John,Kilby Jonathan,Cutteridge Joseph,Jeffery Katie,Lillie Katy,Turtle Lance,Romaniuk Leigh,Denly Lucy,Hering Luisa,Ansari M. Azim,Pace Matthew,Chand Meera,Carroll Miles,Ali Mohammad,Kasanyinga Mwila,Meardon Naomi,Gillson Natalie,Rongkard Patpong,Klenerman Paul,Goulder Philip,Matthews Philippa,Whitham Rachel,Brown Rebecca,Payne Rebecca,Wilson Robert,Rowland-Jones Sarah,Thomas Sarah,Moore Shona,Gardiner Siobhan,Longet Stephanie,Tucker Stephanie,Dobson Sue,Hopkins Susan,Dunachie Susanna,Adlou Syed,de Silva Thushan,Tipton Tom,Hall Victoria,James William,Lawrie Allan,Smith Nikki,Turton Helena,Zawia Amira,Bayley Martin,Fairman Alex,Harrington Kate,Kirk Rosemary,Marsh Louise,Watson Lisa,Wood Steven,Diffey Benjamin,Jones Chris,Lett Lauren,Platt Gareth,Subramaniam Krishanthi,Wootton Daniel,Payne Brendan,Hambleton Sophie,Kelly Sinead,Marston Judith,Poolan Sonia,Turner Dianne,Haniffa Muzlifah,Stephenson Emily,Adele Sandra,Akhter Hossain Delowar,Chinnakannan Senthil,de Lara Catherine,Donnison Timothy,Hackstein Carl-Philipp,Lee Lian,Lim Nicholas,Malone Tom,Phillips Eloise,Ramamurthy Narayan,Robinson Nichola,Sampson Oliver,Eyre David,Simmons Beatrice,Stafford Lizzie,Mentzer Alexander,Amini Ali,Arancibia-Cárcamo Carolina,Provine Nicholas,Travis Simon,Dimitriadis Stavros,Johnson Sile,Foulkes Sarah,Khawam Jameel,Wellington Edgar,Gilbert-Jaramillo Javier,Knight Michael,Dupont Maeva,Horner Emily,Thaventhiran James,Chalk Jeremy

Funder

Wellcome Trust

Publisher

Elsevier BV

Subject

Virology,Infectious Diseases,Microbiology (medical),Microbiology

Reference27 articles.

1. BNT162b2 mRNA Covid-19 vaccine in a nationwide mass vaccination setting;Dagan;N Engl J Med,2021

2. Effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines on covid-19 related symptoms, hospital admissions, and mortality in older adults in England: test negative case-control study;Lopez Bernal;BMJ,2021

3. Impact of vaccination on new SARS-CoV-2 infections in the United Kingdom;Pritchard;Nat Med,2021

4. Do antibody positive healthcare workers have lower SARS-CoV-2 infection rates than antibody negative healthcare workers? Large multi-centre prospective cohort study (the SIREN study), England: June to November 2020;Hall;medRxiv,2021

5. COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study;Hall;Lancet,2021

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