Smooth muscle-generated methylglyoxal impairs endothelial cell-mediated vasodilatation of cerebral microvessels in type 1 diabetic rats

Author:

Alomar Fadhel12,Singh Jaipaul3,Jang Hee-Seong4,Rozanzki George J45,Shao Chun Hong1,Padanilam Babu J4,Mayhan William G6,Bidasee Keshore R175

Affiliation:

1. Department of Pharmacology and Experimental Neuroscience; University of Nebraska Medical Center; Omaha NE USA

2. Department of Pharmacology; University of Dammam; Dammam Saudi Arabia

3. School of Forensic and Applied Science; University of Central Lancashire; Preston UK

4. Department of Cellular and Integrative Physiology; University of Nebraska Medical Center; Omaha NE USA

5. Nebraska Redox Biology Center; Lincoln NE USA

6. Department of Basic Biomedical Sciences, Sanford School of Medicine; University of South Dakota; Vermillion SD USA

7. Department of Environmental, Agricultural and Occupational Health; University of Nebraska Medical Center; Omaha NE USA

Publisher

Wiley

Subject

Pharmacology

Reference64 articles.

1. The Concise Guide to PHARMACOLOGY 2015/16: Overview;Alexander;Br J Pharmacol,2015a

2. The Concise Guide to PHARMACOLOGY 2015/16: Enzymes;Alexander;Br J Pharmacol,2015b

3. Alomar F 2014 Glyoxalase-1 gene transfer to prevent cerebral microvascular and neuronal dysfunctions in type 1 diabetes mellitus PhD thesis

4. Diagnosis and classification of diabetes mellitus;American Diabetes Association;Dia Care,2010

5. Chronic resveratrol treatment restores vascular responsiveness of cerebral arterioles in type 1 diabetic rats;Arrick;Am J Physiol Heart Circ Physiol,2011

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