The mitochondrial fluorescent dye rhodamine 123 is a high-affinity substrate for organic cation transporters (OCTs) 1 and 2-Reference-Cited by-同舟云学术

The mitochondrial fluorescent dye rhodamine 123 is a high-affinity substrate for organic cation transporters (OCTs) 1 and 2

Published:2012-08-23 Issue:1 Volume:28 Page:65-77
ISSN:0767-3981
Container-title:Fundamental & Clinical Pharmacology
language:en
Short-container-title:Fundam Clin Pharmacol

Author:

Jouan Elodie¹,Le Vee Marc¹,Denizot Claire²,Da Violante Georges²,Fardel Olivier¹³

Affiliation:

1. Institut de Recherches en Santé, Environnement et Travail (IRSET), UMR INSERM U1085, Faculté de Pharmacie; 2 Avenue du Pr Léon Bernard 35043 Rennes France

2. Technologie Servier; 25-27 rue Eugène Vignat 45000 Orléans France

3. Pôle Biologie; Centre Hospitalier Universitaire; 2 rue Henri Le Guilloux 35033 Rennes France

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/j.1472-8206.2012.01071.x/fullpdf

Reference57 articles.

1. Localization of mitochondria in living cells with rhodamine 123;Johnson;Proc. Natl. Acad. Sci. USA,1980

2. Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy;Johnson;J. Cell Biol.,1981

3. Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells;Chaudhary;Cell,1991

4. The P-glycoprotein multidrug transporter;Fardel;Gen. Pharmacol.,1996

5. Reciprocal correlation between expression of P-glycoprotein and accumulation of rhodamine 123 in human tumors;Efferth;Anticancer Res.,1989

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