YH12852, a Potent and Selective Receptor Agonist of 5‐hydroxytryptamine, Increased Gastrointestinal Motility in Healthy Volunteers and Patients With Functional Constipation-Reference-Cited by-同舟云学术

YH12852, a Potent and Selective Receptor Agonist of 5‐hydroxytryptamine, Increased Gastrointestinal Motility in Healthy Volunteers and Patients With Functional Constipation

Published:2020-11-30 Issue:2 Volume:14 Page:625-634
ISSN:1752-8054
Container-title:Clinical and Translational Science
language:en
Short-container-title:Clin Transl Sci

Author:

Lee Hyun A.¹²,Ju Moon Seol³,Yoo Hyounggyoon¹,Kyung Kim Mi⁴,Bok Jang Seong⁴,Lee Seoungoh⁴,Kim Sohee⁴,Lee Howard¹²⁵

Affiliation:

1. Department of Clinical Pharmacology and Therapeutics Seoul National University College of Medicine and Hospital Seoul Korea

2. Department of Transdisciplinary Studies Graduate School of Convergence Science and Technology Seoul National University Seoul Korea

3. Center for Clinical Pharmacology Biomedical Research Institute Chonbuk National University Hospital Jeonju Korea

4. Yuhan Research & Development Institute Yuhan Corporation Seoul Korea

5. Department of Molecular Medicine and Biopharmaceutical Sciences Graduate School of Convergence Science and Technology Seoul National University Seoul Korea

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Biochemistry, Genetics and Molecular Biology,General Medicine,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cts.12924

Reference40 articles.

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2. Efficacy and safety of laxatives for chronic constipation in long‐term care settings: A systematic review

3. Mechanisms, Evaluation, and Management of Chronic Constipation

4. Cumulative incidence of chronic constipation: a population-based study 1988-2003

5. Role of prucalopride, a serotonin (5‐HT4) receptor agonist, for the treatment of chronic constipation;Wong B.S.;Clin. Exp. Gastroenterol.,2010

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1. Pharmacologic treatment of gastroparesis: What is (still) on the horizon?;Current Opinion in Pharmacology;2023-10

2. A population pharmacokinetic‐pharmacodynamic model of YH12852, a highly selective 5‐hydroxytryptamine 4 receptor agonist, in healthy subjects and patients with functional constipation;CPT: Pharmacometrics & Systems Pharmacology;2021-07-03