A population pharmacokinetic‐pharmacodynamic model of YH12852, a highly selective 5‐hydroxytryptamine 4 receptor agonist, in healthy subjects and patients with functional constipation-Reference-Cited by-同舟云学术

A population pharmacokinetic‐pharmacodynamic model of YH12852, a highly selective 5‐hydroxytryptamine 4 receptor agonist, in healthy subjects and patients with functional constipation

Published:2021-07-03 Issue:8 Volume:10 Page:902-913
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacometrics Syst. Pharmacol.

Author:

Kim Siun¹²^ORCID,Lee Hyun A.¹²,Jang Seong Bok³,Lee Howard¹²⁴⁵⁶^ORCID

Affiliation:

1. Department of Applied Biomedical Engineering Graduate School of Convergence Science and Technology Seoul National University Seoul Korea

2. Department of Molecular Medicine and Biopharmaceutical Sciences Graduate School of Convergence Science and Technology Seoul National University Seoul Korea

3. Clinical Development Department Research & Development Division Yuhan Corporation Seoul Korea

4. Department of Clinical Pharmacology and Therapeutics Seoul National University College of Medicine and Hospital Seoul Korea

5. Department of Clinical Pharmacology and Therapeutics Seoul National University Hospital Seoul Korea

6. Center for Convergence Approaches in Drug Development Seoul National University Seoul Korea

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12664

Reference25 articles.

1. Bowel Disorders

2. Prevalence of, and Risk Factors for, Chronic Idiopathic Constipation in the Community: Systematic Review and Meta-analysis

3. Impact of Chronic Constipation on Health-Related Quality of Life, Work Productivity, and Healthcare Resource Use: An Analysis of the National Health and Wellness Survey

4. Guidelines for the Diagnosis and Treatment of Chronic Functional Constipation in Korea, 2015 Revised Edition

5. Clinical practice guidelines for the management of constipation in adults. Part 2: Diagnosis and treatment;Serra J;Gastroenterología y Hepatología (English Edition),2017

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