Blockade by polyamine NMDA antagonists related to ifenprodil of NMDA-induced synthesis of cyclic GMP, increases in calcium and cytotoxicity in cultured neurones

Author:

Beart Philip M.,Schousboe Arne,Frandsen Aase

Publisher

Wiley

Subject

Pharmacology

Reference56 articles.

1. Pharmacological actions of ifenprodil in the rat isolated anococcygeus muscle;ADEAGBO;J. Pharm. Pharmacol.,1985

2. Polyamine-sensitive binding of [125I]ifenprodil in washed, frozenthawed synaptic membranes: evidence for high affinity binding requiring an open NMD A channel;BEART;Neurosci. Lett.,1992a

3. [125I]ifenprodil, a convenient radioligand for binding and autoradiographic studies of the polyamine-sensitive site of the NMDA receptor;BEART;Neurosci. Lett.,1991

4. Polyamine NMDA antagonist including a novel series of heterocyclic amino alcohols: evidence for a common site of interaction with antitussive and sigma drugs;BEART;Mol. Neuropharmacol.,1992b

5. Novel aminoalcohols related to ifenprodil possess sigma and neuroprotective activity;BEART;Br. J. Pharmacol.,1993a

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