Antinociceptive activity of the tachykinin NK1 receptor antagonist, CP-99,994, in conscious gerbils

Author:

Rupniak N.M.J.,Webb J.K.,Williams A.R.,Carlson E.,Boyce S.,Hill R.G.

Publisher

Wiley

Subject

Pharmacology

Reference32 articles.

1. Investigation into species variants in tachykinin NKi receptors by use of the non-peptide antagonist, CP-96,345;BERESFORD;Br. J. Pharmacol.,1991

2. The non-peptide NK1 receptor antagonist, (±)-CP-96,345, produces antinociceptive and anti-oedema effects in the rat;BIRCH;Br. J. Pharmacol.,1992

3. BOYCE , S. LAIRD , J.M.A. TATTERSALL , F.D. RUPNIAK , N.M.J. HARGREAVES , R.J. HILL , R.G. 1993 Antinociceptive effects of NKI receptor antagonists: comparison of behavioural and electrophysiological tests I.A.S.P. Publications Congress Abstracts , p 231

4. The effect of intrathecal administration of RP67580, a potent neurokinin 1 antagonist, on nociceptive transmission in the rat spinal cord;CHAPMAN;Neurosci. Letts.,1993

5. Substance P-mediated slow excitatory postsynaptic potential elicited in dorsal horn neurones in vivo by noxious stimulation;KONINCK;Proc. Natl. Acad. Sci. U.S.A.,1991

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