Quantitative Detection and Genotyping ofHelicobacter pylorifrom Stool using Droplet Digital PCR Reveals Variation in Bacterial Loads that Correlates withcagAVirulence Gene Carriage

Author:

Talarico Sarah1,Safaeian Mahboobeh2,Gonzalez Paula34,Hildesheim Allan2,Herrero Rolando34,Porras Carolina3,Cortes Bernal3,Larson Ann56,Fang Ferric C.567,Salama Nina R.17

Affiliation:

1. Division of Human Biology; Fred Hutchinson Cancer Research Center; Seattle WA USA

2. National Cancer Institute; NIH; Rockville MD USA

3. Proyecto Epidemiológico Guanacaste; Fundación INCIENSA; Guanacaste Costa Rica

4. International Agency for Research on Cancer; Lyon France

5. Clinical Microbiology Laboratory; Harborview Medical Center; Seattle WA USA

6. Department of Laboratory Medicine; University of Washington; Seattle WA USA

7. Department of Microbiology; University of Washington; Seattle WA USA

Funder

National Institutes of Health

NIH Intramural Research Program

Publisher

Wiley

Subject

Infectious Diseases,Gastroenterology,General Medicine

Reference41 articles.

1. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012;Ferlay;Int J Cancer,2015

2. Global burden of gastric cancer attributable to Helicobacter pylori;Plummer;Int J Cancer,2015

3. An inverse relation between cagA+ strains of Helicobacter pylori infection and risk of esophageal and gastric cardia adenocarcinoma;Chow;Cancer Res,1998

4. Helicobacter pylori infection and the risk of development of esophageal adenocarcinoma;Martel;J Infect Dis,2005

5. Helicobacter pylori colonization is inversely associated with childhood asthma;Chen;J Infect Dis,2008

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