Up‐regulation of paired‐related homeobox 2 promotes cardiac fibrosis in mice following myocardial infarction by targeting of Wnt5a

Author:

Bai Wen‐Wu12,Tang Zhen‐Yu3,Shan Ti‐Chao4,Jing Xue‐Jiao5,Li Peng6,Qin Wei‐Dong4ORCID,Song Ping6,Wang Bo2,Xu Jian6,Liu Zhan7ORCID,Yu Hai‐Ya8,Ma Zhi‐Min9,Wang Shuang‐Xi16ORCID,Liu Chao810,Guo Tao1ORCID

Affiliation:

1. The Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of Education Chinese National Health Commission and Chinese Academy of Medical Sciences The State and Shandong Province Joint Key Laboratory of Translational Cardiovascular Medicine Qilu Hospital of Shandong University Jinan China

2. Department of Traditional Chinese Medicine Qilu Hospital of Shandong University Jinan China

3. Department of Emergency Qilu Hospital of Shandong University Jinan China

4. Department of Critical Care Medicine Qilu Hospital of Shandong University Jinan China

5. Department of Geriatric Medicine Qilu Hospital of Shandong University, Key Laboratory of Cardiovascular Proteomics of Shandong Province Qilu Hospital of Shandong University Jinan China

6. Department of Pharmacology College of Pharmacy Xinxiang Medical University Xinxiang China

7. Department of Gastroenterology and Clinical Nutrition The First Affiliated Hospital of Hunan Normal University Changsha China

8. Department of Neurology The People’s Hospital of Xishui County Huangang China

9. Department of Endocrinology The Affiliated Suzhou Science & Technology Town Hospital of Nanjing Medical University Suzhou China

10. Hubei Key Laboratory of Cardiovascular, Cerebrovascular, and Metabolic Disorders Hubei University of Science and Technology Xianning China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

China Postdoctoral Science Foundation

Publisher

Wiley

Subject

Cell Biology,Molecular Medicine

Reference43 articles.

1. Depression and coronary heart disease

2. Intracellular acidosis via activation of Akt-Girdin signaling promotes post ischemic angiogenesis during hyperglycemia

3. Cardiac Fibroblast

4. Cardiac Fibrosis

5. HOTAIR promotes myocardial fibrosis through regulating URI1 expression via Wnt pathway;Pan SC;Eur Rev Med Pharmacol Sci,2018

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