Identification of a novel <scp>QTL</scp> for lean meat percentage using imputed genotypes-Reference-Cited by-同舟云学术

Identification of a novel QTL for lean meat percentage using imputed genotypes

Published:2024-05-16 Issue:4 Volume:55 Page:658-663
ISSN:0268-9146
Container-title:Animal Genetics
language:en
Short-container-title:Animal Genetics

Author:

Ibragimov Emil¹^ORCID,Pedersen Anni Øyan¹,Sloth Niels Morten²,Fredholm Merete¹^ORCID,Karlskov‐Mortensen Peter¹^ORCID

Affiliation:

1. Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences University of Copenhagen Frederiksberg Denmark

2. SEGES Danish Pig Research Center Aarhus Denmark

Abstract

AbstractLean meat percentage is a critical production trait in pig breeding systems with direct implications for the sustainability of the industry. In this study, we conducted a genome‐wide association study for lean meat percentage using a cohort of 850 Duroc × (Landrace × Yorkshire) crossbred pigs and we identified QTL on SSC3 and SSC18. Based on the predicted effect of imputed variants and using the PigGTEx database of molecular QTL, we prioritized candidate genes and SNPs located within the QTL regions, which may be involved in the regulation of porcine leanness. Our results indicate that a nonsense mutation in ZC3HAV1L on SSC18 has a direct effect on lean meat percentage.

Funder

Fødevarestyrelsens

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/age.13442

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