Exposure-response characterization of tofacitinib efficacy in moderate to severe ulcerative colitis: Results from a dose-ranging phase 2 trial
Author:
Affiliation:
1. Pfizer Inc; Groton CT USA
2. Pfizer Inc; Collegeville PA USA
3. Pfizer Inc; Sandwich UK
4. Projections Research Inc; Phoenixville PA USA
Funder
Pfizer
Publisher
Wiley
Subject
Pharmacology (medical),Pharmacology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.13523/fullpdf
Reference19 articles.
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2. Inflammatory bowel disease: clinical aspects and established and evolving therapies;Baumgart;Lancet,2007
3. Course of ulcerative colitis: analysis of changes in disease activity over years;Langholz;Gastroenterology,1994
4. Review article: remission rates achievable by current therapies for inflammatory bowel disease;Peyrin-Biroulet;Aliment Pharmacol Ther,2011
5. Loss of response and requirement of infliximab dose intensification in Crohn's disease: a review;Gisbert;Am J Gastroenterol,2009
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