Selective Inhibitors of Janus Kinase 3 Modify Responses to Lipopolysaccharides by Increasing the Interleukin-10-to-Tumor Necrosis Factor α Ratio-Reference-Cited by-同舟云学术

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Selective Inhibitors of Janus Kinase 3 Modify Responses to Lipopolysaccharides by Increasing the Interleukin-10-to-Tumor Necrosis Factor α Ratio

Published:2023-05-18 Issue:6 Volume:6 Page:892-906
ISSN:2575-9108
Container-title:ACS Pharmacology & Translational Science
language:en
Short-container-title:ACS Pharmacol. Transl. Sci.

Author:

Laux Julian¹²,Martorelli Mariella¹²,Späth Nadja¹,Maier Florian¹,Burnet Michael¹^ORCID,Laufer Stefan A.²³⁴^ORCID

Affiliation:

1. Synovo GmbH, Paul-Ehrlich-Straße 15, 72076 Tübingen, DE, Germany

2. Department of Pharmaceutical/Medicinal Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, DE, Germany

3. Cluster of Excellence iFIT (EXC 2180) “Image-Guided and Functionally Instructed Tumor Therapies”, University of Tübingen, 72076 Tübingen, Germany

4. Tübingen Center for Academic Drug Discovery & Development (TüCAD2), 72076 Tübingen, Germany

Funder

Bundesministerium f?r Bildung und Forschung

Deutsche Forschungsgemeinschaft

Baden-W?rttemberg Stiftung

Publisher

American Chemical Society (ACS)

Subject

Pharmacology (medical),Pharmacology

Link

https://pubs.acs.org/doi/pdf/10.1021/acsptsci.3c00043

Reference87 articles.

1. The JAK/STAT signaling pathway

2. JAK/STAT Pathways in Cytokine Signaling and Myeloproliferative Disorders: Approaches for Targeted Therapies

3. JAKS AND STATS: Biological Implications

4. Jak3 negatively regulates dendritic-cell cytokine production and survival

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