Design and pharmacological characterization of VUF14480, a covalent partial agonist that interacts with cysteine 983.36of the human histamine H4receptor-Reference-Cited by-同舟云学术

Design and pharmacological characterization of VUF14480, a covalent partial agonist that interacts with cysteine 983.36of the human histamine H4receptor

Published:2013-08-15 Issue:1 Volume:170 Page:89-100
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:Br J Pharmacol

Author:

Nijmeijer S¹,Engelhardt H,Schultes S,van de Stolpe A C¹,Lusink V¹,de Graaf C¹,Wijtmans M¹,Haaksma E E J²,de Esch I J P¹,Stachurski K²,Vischer H F¹,Leurs R¹

Affiliation:

1. Division of Medicinal Chemistry; Faculty of Sciences; Amsterdam Institute for Molecules, Medicines and Systems (AIMMS); VU University Amsterdam; Amsterdam; The Netherlands

2. Department of Medicinal Chemistry; Boehringer Ingelheim RCV GmbH & Co KG; Vienna; Austria

Publisher

Wiley

Subject

Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bph.12113/fullpdf

Reference50 articles.

1. Integrated methods for the construction of three dimensional models and computational probing of structure funciton relations in G protein-coupled receptors;Ballesteros;Methods Neurosci,1995

2. Site-specific disulfide capture of agonist and antagonist peptides on the C5a receptor;Buck;J Biol Chem,2005

3. Interactions of the melanocortin-4 receptor with the peptide agonist NDP-MSH;Chapman;J Mol Biol,2010

4. Chavez FCM Edwards JP Gomez L Grice CA Kearney AM Savall BM et al 2008 Benzofuro- and benzothienopyrimidine modulators of the histamine H4 receptor, (Janssen Pharmaceutica NV)

5. Characterization of irreversible binding of beta-funaltrexamine to the cloned rat mu opioid receptor;Chen;J Biol Chem,1995

Cited by 29 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Vinylpyridine as a Tunable Covalent Warhead Targeting C797 in EGFR;ACS Medicinal Chemistry Letters;2024-04-05

2. Pharmacological Characterization and Radiolabeling of VUF15485, a High-Affinity Small-Molecule Agonist for the Atypical Chemokine Receptor ACKR3;Molecular Pharmacology;2024-02-12

3. Pharmacological characterization and radiolabeling of VUF15485, a high-affinity small-molecule agonist for the atypical chemokine receptor ACKR3;MOL PHARMACOL;2023-07-12

4. SAR exploration of the non‐imidazole histamine H ₃ receptor ligand ZEL‐H16 reveals potent inverse agonism;Archiv der Pharmazie;2022-10-30

5. New Chemical Biology Tools for the Histamine Receptor Family;The Functional Roles of Histamine Receptors;2022