Population pharmacokinetics and probability of target attainment in patients with sepsis under renal replacement therapy receiving continuous infusion of meropenem: Sustained low‐efficiency dialysis and continuous veno‐venous haemodialysis

Author:

Westermann Isabella12,Gastine Silke3,Müller Carsten4,Rudolph Wiebke5,Peters Frank5,Bloos Frank12,Pletz Mathias6,Hagel Stefan26ORCID

Affiliation:

1. Department of Anesthesiology and Intensive Care Therapy Jena University Hospital – Friedrich Schiller University Jena Jena Germany

2. Center for Sepsis Control and Care ‐ Friedrich Schiller University Jena Jena Germany

3. Great Ormond Street Institute of Child Health University College London London UK

4. Centre of Pharmacology, Department of Therapeutic Drug Monitoring University of Cologne Cologne Germany

5. Institute of Forensic Medicine Jena University Hospital – Friedrich Schiller University Jena Jena Germany

6. Institute for Infectious Diseases and Infection Control Jena University Hospital – Friedrich Schiller University Jena Jena Germany

Funder

Haridus- ja Teadusministeerium

Universitätsklinikum Jena

Center for Sepsis Control and Care

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference35 articles.

1. Carbapenems

2. Meronem IV ‐ Summary of Product Characteristics (SmPC) ‐ (emc). Accessed January 23 2021.https://www.medicines.org.uk/emc/medicine/11215#gref

3. Meropenem

4. Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'

5. Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper#

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