Antimicrobial pharmacodynamics: critical interactions of 'bug and drug'
Author:
Publisher
Springer Science and Business Media LLC
Subject
General Immunology and Microbiology,Microbiology,Infectious Diseases
Link
http://www.nature.com/articles/nrmicro862.pdf
Reference47 articles.
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2. Preston, S. L. et al. Levofloxacin population pharmacokinetics and creation of a demographic model for prediction of individual drug clearance in patients with serious community-acquired infection. Antimicrob. Agents Chemother. 42, 1098–1104 (1998).
3. Chien, S. -C. et al. Pharmacokinetic profile of levofloxacin following once-daily 500-milligram oral or intravenous doses. Antimicrob. Agents Chemother. 41, 2256–2260 (1997).
4. Eagle, H., Fleischman, R. & Levy, M. Continuous versus discontinuous therapy with penicillin: the effect of interval between injections on therapeutic efficacy. N. Engl. J. Med. 248, 481–488 (1953). The first animal infection study in which pharmacodynamic principles were used.
5. Vogelman, B. et al. Correlation of antimicrobial pharmacokinetic parameters with therapeutic efficacy in an animal model. J. Infect. Dis. 158, 831–847 (1988).
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