Cannabis smoking impairs driving performance on the simulator and real driving: a randomized, double-blind, placebo-controlled, crossover trial

Author:

Micallef Joëlle12ORCID,Dupouey Julien12,Jouve Elisabeth12,Truillet Romain12,Lacarelle Bruno3,Taillard Jacques4,Daurat Agnès5,Authié Colas6,Blin Olivier12,Rascol Olivier7,Philip Pierre4,Mestre Daniel8

Affiliation:

1. Service de Pharmacologie Clinique et Pharmacovigilance & CIC-CPCET; Assistance Publique Hôpitaux de Marseille; 264 Rue Saint Pierre 13385 Marseille France

2. Aix-Marseille Universite Faculté de Médecine; INS - Institut de Neurosciences des Systèmes INSERM UMR 1106 Marseille; Marseille France

3. Laboratoire de Pharmacocinétique et Toxicologie; Assistance Publique Hôpitaux de Marseille; Marseille France

4. Université de Bordeaux, CNRS, Sommeil Attention et Neuropsychiatrie, USR 3413; Bordeaux France

5. Université Toulouse II, CNRS, EPHE, CLLE-LTC UMR 5263; Toulouse France

6. Institut de la Vision, CNRS, UPMC, INSERM, UMR 7210; Paris France

7. Department of Clinical Pharmacology and Neurosciences; Clinical Investigation Center INSERM CIC1436 and Clinique Spatiale MEDES; University Hospital and University of Toulouse3; Toulouse France

8. Aix-Marseille Université, CNRS, Institut des Sciences du Mouvement, UMR 7287; Marseille France

Funder

Agence Nationale de la Recherche

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Reference50 articles.

1. World Health Organization Global status report on road safety 2015

2. Prolonged nocturnal driving can be as dangerous as severe alcohol-impaired driving;Verster;J. Sleep Res.,2011

3. A case-control study estimating accident risk for alcohol, Medicines and Illegal Drugs;Kuypers;PLoS One,2012

4. Trends in drug use among drivers killed in U.S. traffic crashes, 1999-2010;Rudisill;Accid. Anal. Prev.,2014

5. EMCDDA Driving Under the Influence of Drugs, Alcohol and Medicines in Europe 2012

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