Kinetic and structural characterization of amyloid-β peptide hydrolysis by human angiotensin-1-converting enzyme

Author:

Larmuth Kate M.1,Masuyer Geoffrey2,Douglas Ross G.1,Schwager Sylva L.1,Acharya K. Ravi2,Sturrock Edward D.1

Affiliation:

1. Department of Integrative Biomedical Sciences; Institute of Infectious Disease and Molecular Medicine; University of Cape Town; South Africa

2. Department of Biology and Biochemistry; University of Bath; UK

Funder

Medical Research Council

National Research Foundation

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference77 articles.

1. The preparation and function of the hypertensin-converting enzyme;Skeggs;J Exp Med,1956

2. Ace revisited: a new target for structure-based drug design;Acharya;Nat Rev Drug Discov,2003

3. A dipeptidyl carboxypeptidase that converts angiotensin I and inactivates bradykinin;Yang;Biochim Biophys Acta,1970

4. Two putative active centers in human angiotensin I-converting enzyme revealed molecular cloning;Soubrier;Proc Natl Acad Sci USA,1988

5. The two homologous domains of human angiotensin I-converting enzyme are both catalytically active;Wei;J Biol Chem,1991

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