Synthesis and Antimicrobial Activity of 4-Chloro-3-Nitrophenylthiourea Derivatives Targeting Bacterial Type II Topoisomerases-Reference-Cited by-同舟云学术

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Synthesis and Antimicrobial Activity of 4-Chloro-3-Nitrophenylthiourea Derivatives Targeting Bacterial Type II Topoisomerases

Published:2016-02-11 Issue:6 Volume:87 Page:905-917
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Bielenica Anna¹,Stępień Karolina²,Napiórkowska Agnieszka³,Augustynowicz-Kopeć Ewa³,Krukowski Sylwester⁴,Włodarczyk Marta⁵,Struga Marta⁵

Affiliation:

1. Chair and Department of Biochemistry; Medical University; 02-097 Warszawa Poland

2. Department of Pharmaceutical Microbiology; Medical University; 02-007 Warszawa Poland

3. Department of Microbiology; National Tuberculosis and Lung Diseases Research Institute; 01-138 Warszawa Poland

4. Department of Inorganic and Analytical Chemistry; Faculty of Pharmacy; Medical University; 02-097 Warszawa Poland

5. Department of Pharmacogenomics; Faculty of Pharmacy; Medical University; 02-097 Warszawa Poland

Funder

European Union - the European Regional Development Fund

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12723/fullpdf

Reference34 articles.

1. Peptides based on CcdB protein as novel inhibitors of bacterial topoisomerases;Trovatti;Bioorg Med Chem Lett,2008

2. Novel compounds targeting bacterial DNA topoisomerase/DNA gyrase;Ehmann;Curr Opin Pharmacol,2014

3. Inhibition of DNA gyrase and DNA topoisomerase IV of Staphylococcus aureus and Escherichia coli by aminocoumarin antibiotics;Alt;J Antimicrob Chemother,2011

4. Fragment-to-hit-to-lead discovery of a novel pyridylurea scaffold of ATP competitive dual targeting type II topoisomerase inhibiting antibacterial agents;Basarab;J Med Chem,2013

5. Evaluation of WO2012177707 and WO2012097269: vertex's phosphate prodrugs of gyrase and topoisomerase antibacterial agents;Finn;Expert Opin Ther Pat,2013

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2. Proapoptotic effects of halogenated bis‐phenylthiourea derivatives in cancer cells;Archiv der Pharmazie;2023-07-04

3. Synthesis, Structural Characterization and Biological Activity Evaluation of Novel Cu(II) Complexes with 3-(trifluoromethyl)phenylthiourea Derivatives;International Journal of Molecular Sciences;2022-12-10

4. Synthesis, Antibacterial Activity, and Molecular Docking Study of Bispyrazole‐Based Derivatives as Potential Antibacterial Agents;ChemistrySelect;2022-01-26

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