Fragment-to-Hit-to-Lead Discovery of a Novel Pyridylurea Scaffold of ATP Competitive Dual Targeting Type II Topoisomerase Inhibiting Antibacterial Agents-Reference-Cited by-同舟云学术

Fragment-to-Hit-to-Lead Discovery of a Novel Pyridylurea Scaffold of ATP Competitive Dual Targeting Type II Topoisomerase Inhibiting Antibacterial Agents

Published:2013-10-29 Issue:21 Volume:56 Page:8712-8735
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Basarab Gregory S.¹,Manchester John I.¹,Bist Shanta¹,Boriack-Sjodin P. Ann¹,Dangel Brian¹,Illingworth Ruth¹,Sherer Brian A.¹,Sriram Shubha¹,Uria-Nickelsen Maria¹,Eakin Ann E.¹

Affiliation:

1. Infection Innovative Medicines, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401208b

Reference73 articles.

1. New antimicrobial agents on the horizon

2. Challenges of Antibacterial Discovery

3. Discovery of novel antibacterials

4. The global need for effective antibiotics: challenges and recent advances

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