Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1-Reference-Cited by-同舟云学术

Metabolic activation and analgesic effect of flupirtine in healthy subjects, influence of the polymorphic NAT2, UGT1A1 and GSTP1

Published:2015-02-20 Issue:3 Volume:79 Page:501-513
ISSN:0306-5251
Container-title:British Journal of Clinical Pharmacology
language:en
Short-container-title:Br J Clin Pharmacol

Author:

Siegmund Werner¹,Modess Christiane¹,Scheuch Eberhard¹,Methling Karen²,Keiser Markus¹,Nassif Ali¹,Rosskopf Dieter³,Bednarski Patrick J.⁴,Borlak Jürgen⁵,Terhaag Bernd⁶

Affiliation:

1. Department of Clinical Pharmacology; University Medicine Greifswald; Greifswald Germany

2. Department of Biochemistry; University of Greifswald; Greifswald Germany

3. Department of Pharmacology of the Center of Drug Absorption and Transport (C_DAT); University Medicine Greifswald; Greifswald Germany

4. Department of Pharmaceutical and Medicinal Chemistry; University of Greifswald; Greifswald Germany

5. Centre for Pharmacology and Toxicology; Hannover Medical School; Hannover Germany

6. Medical Consultant; Dresden Germany

Funder

AWD.pharma GmbH & Co. KG, Radebeul, Germany

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/bcp.12522/fullpdf

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