OCT2013, an ischaemia‐activated antiarrhythmic prodrug, devoid of the systemic side effects of lidocaine-Reference-Cited by-同舟云学术

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OCT2013, an ischaemia‐activated antiarrhythmic prodrug, devoid of the systemic side effects of lidocaine

Published:2022-01-13 Issue: Volume: Page:
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:British J Pharmacology

Author:

Hesketh Louise M.¹,Sikkel Markus B.²,Mahoney‐Sanchez Laura¹,Mazzacuva Francesca³,Chowdhury Rasheda A.²,Tzortzis Konstantinos N.²,Firth Jahn²,Winter James¹,MacLeod Kenneth T.²,Ogrodzinski Stefan⁴,Wilder Catherine D. E.¹,Patterson Laurence H.⁴,Peters Nicholas S.²,Curtis Michael J.¹^ORCID

Affiliation:

1. Cardiovascular Division, Faculty of Life Sciences and Medicine, The Rayne Institute, St Thomas' Hospital King's College London London UK

2. National Heart and Lung Institute, Faculty of Medicine, ICTEM, The Hammersmith Hospital Imperial College London London UK

3. Mass Spectrometry Facility King's College London London UK

4. BioTherics Ltd Shepshed UK

Funder

Medical Research Council

Instytut Biologii Medycznej Polskiej Akademii Nauk

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bph.15764

Reference60 articles.

1. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels

2. Feasibility of targeting ischaemia-related ventricular arrhythmias by mimicry of endogenous protection by endocannabinoids

3. Better antiarrhythmics? Development of antiarrhythmic drugs selective for ischaemia-dependent arrhythmias

4. Lack of selectivity for ventricular and ischaemic tissue limits the antiarrhythmic actions of lidocaine, quinidine and flecainide against ischaemia-induced arrhythmias

5. Ischaemia selectivity confers efficacy for suppression of ischaemia-induced arrhythmias in rats

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2. Automated fabrication of a scalable heart-on-a-chip device by 3D printing of thermoplastic elastomer nanocomposite and hot embossing;Bioactive Materials;2024-03

3. Research Progress on the Mechanism of Lidocaine Affecting Myocardial Ischemia-Reperfusion Injury;Advances in Clinical Medicine;2024

4. One-step fabrication of lidocaine/CalliSpheres® composites for painless transcatheter arterial embolization;Journal of Translational Medicine;2022-10-11

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