Natural product pharmacology: the British Journal of Pharmacology perspective

Author:

Wang Xin1ORCID,Izzo Angelo A.2,Papapetropoulos Andreas34ORCID,Alexander Steve P. H.5ORCID,Cortese‐Krott Miriam67ORCID,Kendall Dave A.5ORCID,Martemyanov Kirill A.8,Mauro Claudio9,Panettieri Reynold A.10ORCID,Patel Hemal H.11ORCID,Schulz Rainer12,Stefanska Barbara13,Stephens Gary J.14ORCID,Teixeira Mauro M.15ORCID,Vergnolle Nathalie16ORCID,Ferdinandy Péter1718

Affiliation:

1. Faculty of Biology, Medicine and Health University of Manchester Manchester UK

2. Department of Pharmacy University of Naples Federico II Naples Italy

3. Laboratory of Pharmacology, Department of Pharmacy National and Kapodistrian University of Athens Athens Greece

4. Clinical Experimental Surgery and Translational Research Center Biomedical Research Foundation of the Academy of Athens Athens Greece

5. University of Nottingham Nottingham UK

6. Myocardial Infarction Research Laboratory, Department of Cardiology, Pneumology, Angiology, Medical Faculty Heinrich Heine University of Düsseldorf Düsseldorf Germany

7. CARID, Cardiovascular Research Institute Düsseldorf Düsseldorf Germany

8. Department of Neuroscience, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology University of Florida Jupiter Florida USA

9. Institute of Inflammation and Ageing, College of Medical and Dental Sciences University of Birmingham Birmingham UK

10. Rutgers University New Brunswick New Jersey USA

11. VA San Diego Healthcare System and University of California/San Diego San Diego California USA

12. University of Giessen Giessen Germany

13. University of British Columbia Vancouver British Columbia Canada

14. University of Reading Reading UK

15. Federal University of Minas Gerais Belo Horizonte Brazil

16. IRSD, Université de Toulouse, INSERM, INRAE, ENVT, UPS Toulouse France

17. Department of Pharmacology and Pharmacotherapy Semmelweis University Budapest Hungary

18. Pharmahungary Group Szeged Hungary

Abstract

Natural products (NPs) have long been used as a rich source of bioactive compounds for drug development. Recent technological advancements have revitalised natural products research as evidenced by increased publications in this field. In this editorial review, we highlight key points from the 2020 British Journal of Pharmacology (BJP) practical guide, which outlines standards for natural products research reports, and provide papers published in BJP between years 2020 to 2023 that demonstrate adherence to these guidelines. Looking ahead, we discuss the potential of chemical proteomics approaches to elucidate natural products mechanisms of action and identify therapeutic targets for future research. By fostering innovation, we aim to advance natural products research and contribute to the development of novel therapeutics that will have a significant impact on healthcare.

Publisher

Wiley

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