Structure-activity relationship studies of benzyl-, phenethyl-, and pyridyl-substituted tetrahydroacridin-9-amines as multitargeting agents to treat Alzheimer's disease-Reference-Cited by-同舟云学术

Structure-activity relationship studies of benzyl-, phenethyl-, and pyridyl-substituted tetrahydroacridin-9-amines as multitargeting agents to treat Alzheimer's disease

Published:2016-07-11 Issue:5 Volume:88 Page:710-723
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Osman Wesseem¹,Mohamed Tarek¹²,Sit Victor Munsing¹,Vasefi Maryam S.¹,Beazely Michael A.¹,Rao Praveen P. N.¹

Affiliation:

1. School of Pharmacy; Health Sciences Campus; University of Waterloo; Waterloo ON Canada

2. Department of Chemistry; University of Waterloo; Waterloo ON Canada

Funder

Natural Sciences and Engineering Research Council of Canada

Canada Foundation for Innovation

Ontario Research Fund(ORF)

ERA

Ministry of Research and Innovation

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12800/fullpdf

Reference45 articles.

1. The cholinergic system in aging and neuronal degeneration

2. Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications

3. Therapeutic strategies for Alzheimer's disease

4. The Molecular Forms of Cholinesterase and Acetylcholinesterase in Vertebrates

5. Acetylcholinesterase — new roles for an old actor

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Design, synthesis and structure-activity relationship studies of 3-phenylpyrazino[1,2-a]indol-1(2H)-ones as amyloid aggregation and cholinesterase inhibitors with antioxidant activity;European Journal of Medicinal Chemistry Reports;2022-12

2. Recent Advances in the Synthesis of Tacrine Derivatives as Multifunctional Agents for Alzheimer's Disease;Current Organic Chemistry;2021-12-02

3. Molecular Docking and Recent Advances in the Design and Development of Cholinesterase Inhibitor Scaffolds: Coumarin Hybrids;ChemistrySelect;2019-12-20

4. Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors;European Journal of Medicinal Chemistry;2019-11

5. Novel tacrine-coumarin hybrids linked to 1,2,3-triazole as anti-Alzheimer’s compounds: In vitro and in vivo biological evaluation and docking study;Bioorganic Chemistry;2019-03