Tacrine-O-protected phenolics heterodimers as multitarget-directed ligands against Alzheimer's disease: Selective subnanomolar BuChE inhibitors

Author:

Roldán-Peña Jesús M.,Romero-Real Valle,Hicke Javier,Maya Inés,Franconetti AntonioORCID,Lagunes Irene,Padrón José M.ORCID,Petralla Sabrina,Poeta Eleonora,Naldi Marina,Bartolini ManuelaORCID,Monti Barbara,Bolognesi Maria L.ORCID,López Óscar,Fernández-Bolaños José G.

Funder

Dirección General de Investigación of Spain

Junta de Andalucía

FEDER

Ministry of Education, Universities and Research

MIUR

University of Bologna

COST Action Multi-target paradigm for innovative ligand identification in the drug discovery process

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference40 articles.

1. Über einen eigenartigen schweren ErkrankungsprozeB der Hirnrinde;Alzheimer;Neurologisches Centralblatt,1906

2. Alzheimer's disease: the challenge of the second century;Holtzman;Sci. Transl. Med.,2011

3. Signs and symptoms preceding the diagnosis of Alzheimer's disease: a systematic scoping review of literature from 1937 to 2016;Bature;BMJ Open,2017

4. A review on Alzheimer's disease pathophysiology and its management: an update;Kumar;Pharmacol. Rep.,2015

5. Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers;Reitz;Biochem. Pharmacol.,2014

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3