Associations of novel genetic variations in the folate-related andARID5Bgenes with the pharmacokinetics and toxicity of high-dose methotrexate in paediatric acute lymphoblastic leukaemia

Author:

Csordas Katalin1,Lautner-Csorba Orsolya2,Semsei Agnes F.2,Harnos Andrea3,Hegyi Marta1,Erdelyi Daniel J.1,Eipel Oliver T.1,Szalai Csaba2,Kovacs Gabor T.1

Affiliation:

1. 2nd Department of Paediatrics; Semmelweis University; Budapest Hungary

2. Deparment of Genetics, Cell- and Immunbiology; Semmelweis University; Budapest Hungary

3. Department of Biomathematics and Informatics; Faculty of Veterinary Science; Szent Istvan University; Budapest Hungary

Funder

NKTH (National Research and Technology)

Publisher

Wiley

Subject

Hematology

Reference49 articles.

1. Categorical Data Analysis

2. ALL IC-BFM Trial Steering Committee 2009 A Randomized Trial of the I-BFM-SG for the Management of Childhood Non-B Acute Lymphoblastic Leukemia ALL IC-BFM Trial Steering Committee Hannover

3. Bates , D. Maechler , M. Bolker , B. 2012 lme4: Linear mixed-effects models using S4 classes. R package version 0.999999-0 http://CRAN.R-project.org/package=lme4

4. Acute lymphoblastic leukaemia: a model for the pharmacogenomics of cancer therapy;Cheok;Nature Reviews Cancer,2006

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