Mechanistic insights into 1-deoxy-d-xylulose 5-phosphate reductoisomerase, a key enzyme of the MEP terpenoid biosynthetic pathway-Reference-Cited by-同舟云学术

Mechanistic insights into 1-deoxy-d-xylulose 5-phosphate reductoisomerase, a key enzyme of the MEP terpenoid biosynthetic pathway

Published:2013-10-24 Issue:22 Volume:280 Page:5896-5905
ISSN:1742-464X
Container-title:FEBS Journal
language:en
Short-container-title:FEBS J

Author:

Li Heng¹,Tian Jie¹,Sun Wei²,Qin Wei¹,Gao Wen-Yun¹

Affiliation:

1. Key Laboratory of Resource Biology and Biotechnology in Western China (Ministry of Education); College of Life Sciences; Northwest University; Xi'an China

2. Key Laboratory of Synthetic and Natural Functional Molecule Chemistry (Ministry of Education); School of Chemistry and Materials Science; Northwest University; Xi'an China

Publisher

Wiley

Subject

Cell Biology,Molecular Biology,Biochemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/febs.12516/fullpdf

Reference40 articles.

1. A 1-deoxy-d-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-d-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis;Takahashi;Proc Natl Acad Sci USA,1998

2. Methylerythritol Phosphate Pathway

3. Isoprenoid biosynthesis as a target for antibacterial and antiparasitic drugs: phosphonohydroxamic acids as inhibitors of deoxyxylulose phosphate reductoisomerase;Kuntz;Biochem J,2005

4. Targeting the methylerythritol phosphate (MEP) pathway for novel antimalarial, antibacterial and herbicidal drug discovery: inhibition of 1-deoxy-d-xylulose-5-phosphate reductoisomerase (DXR) enzyme;Singh;Curr Pharm Design,2007

5. 1-Deoxy-d-xylulose 5-phosphate reductoisomerase: an overview;Proteau;Bioorg Chem,2004

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