PKR knockout in the 5xFAD model of Alzheimer's disease reveals beneficial effects on spatial memory and brain lesions-Reference-Cited by-同舟云学术

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PKR knockout in the 5xFAD model of Alzheimer's disease reveals beneficial effects on spatial memory and brain lesions

Published:2019-03 Issue:3 Volume:18 Page:e12887
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Tible Marion¹,Mouton Liger François¹²,Schmitt Julien³⁴⁵,Giralt Albert⁵⁶⁷,Farid Karim⁸⁹,Thomasseau Sylvie¹,Gourmaud Sarah¹¹⁰,Paquet Claire¹⁹¹¹,Rondi Reig Laure³⁴⁵,Meurs Eliane¹²¹³,Girault Jean‐Antoine⁵⁶⁷,Hugon Jacques¹⁹¹¹

Affiliation:

1. Inserm U1144 Paris France

2. Inserm U1127 Paris France

3. Institut de Biologie Paris Seine CNRS, UMR 8246 Paris France

4. Inserm U1130 Paris France

5. Sorbonne Université Paris France

6. Inserm U839 Paris France

7. Institut du Fer à Moulin Paris France

8. Department of Nuclear Medicine CHU Fort de France Martinique France

9. Center of Cognitive Neurology, Lariboisière Fernand Widal Hospital APHP Paris France

10. Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania

11. Paris Diderot University Paris France

12. Hepacivirus and Innate Immunity Unit Institut Pasteur Paris France

13. CNRS, UMR 3569 Paris France

Funder

Agence Nationale de la Recherche

Publisher

Wiley

Subject

Cell Biology,Aging

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.12887

Reference37 articles.

1. LTP maintenance and its protein synthesis-dependence

2. Cerebral amyloid-β PET with florbetaben (18F) in patients with Alzheimer's disease and healthy controls: a multicentre phase 2 diagnostic study

3. PKR Stimulates NF-κB Irrespective of Its Kinase Function by Interacting with the IκB Kinase Complex

4. Modulation of Tau Phosphorylation by the Kinase PKR: Implications in Alzheimer's Disease

5. Neuroinflammation and Aβ Accumulation Linked To Systemic Inflammation Are Decreased By Genetic PKR Down-Regulation

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