Non‐sedating antihistamines block G‐protein‐gated inwardly rectifying K + channels

Author:

Chen I‐Shan12ORCID,Liu Chang12,Tateyama Michihiro12,Karbat Izhar3,Uesugi Motonari45,Reuveny Eitan3,Kubo Yoshihiro12

Affiliation:

1. Division of Biophysics and Neurobiology, Department of Molecular and Cellular Physiology, National Institute for Physiological SciencesNational Institutes of Natural Sciences Okazaki Japan

2. Department of Physiological Sciences, School of Life ScienceSOKENDAI (The Graduate University for Advanced Studies) Hayama Japan

3. Department of Biomolecular SciencesWeizmann Institute of Science Rehovot Israel

4. Institute for Integrated Cell‐Material Sciences (WPI‐iCeMS)Kyoto University Uji Japan

5. Institute for Chemical ResearchKyoto University Uji Japan

Funder

Japan Society for the Promotion of Science

Publisher

Wiley

Subject

Pharmacology

Reference71 articles.

1. A critical gating switch at a modulatory site in neuronal Kir3 channels;Adney S. K.;The Journal of Neuroscience,2015

2. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: G protein-coupled receptors

3. THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Voltage-gated ion channels

4. In vivo and in vitro interaction of the novel selective histamine H1 receptor antagonist mizolastine with H1 receptors in the rodent;Benavides J.;Arzneimittel‐Forschung,1995

5. Control of channel activity through a unique amino acid residue of a G protein-gated inwardly rectifying K+ channel subunit

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