YH12852, a potent and highly selective 5-HT4 receptor agonist, significantly improves both upper and lower gastrointestinal motility in a guinea pig model of postoperative ileus
Author:
Affiliation:
1. Department of Internal Medicine; Gangnam Severance Hospital; Yonsei University College of Medicine; Seoul Korea
2. Washington University; St. Louis MO USA
3. Yuhan R&D Institute; Yuhan Corporation; Seoul Korea
Funder
Yuhan R&D Institute
Yuhan Corporation
Publisher
Wiley
Subject
Gastroenterology,Endocrine and Autonomic Systems,Physiology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1111/nmo.13094/fullpdf
Reference44 articles.
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2. Alvimopan, a novel, peripherally acting mu opioid antagonist: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial of major abdominal surgery and postoperative ileus;Wolff;Ann Surg,2004
3. Gum chewing reduces ileus after elective open sigmoid colectomy;Schuster;Arch Surg,2006
4. Economic burden of postoperative ileus associated with colectomy in the United States;Iyer;J Manag Care Pharm,2009
5. Reducing the burden of postoperative ileus: evaluating and implementing an evidence-based strategy;Barletta;World J Surg,2014
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