Synthesis and Biological Evaluation of 2-oxo-pyrazine-3-carboxamide-yl Nucleoside Analogues and Their Epimers as Inhibitors of Influenza A Viruses-Reference-Cited by-同舟云学术

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Synthesis and Biological Evaluation of 2-oxo-pyrazine-3-carboxamide-yl Nucleoside Analogues and Their Epimers as Inhibitors of Influenza A Viruses

Published:2014-07-12 Issue:3 Volume:85 Page:245-252
ISSN:1747-0277
Container-title:Chemical Biology & Drug Design
language:en
Short-container-title:Chem Biol Drug Des

Author:

Gao Jingjing¹,Luo Xianjin¹,Li Yuhuan²,Gao Rongmei²,Chen Haifeng³,Ji Dingjue³

Affiliation:

1. School of Chemistry and Chemical Engineering; Shanghai JiaoTong University; Shanghai 200240 China

2. Institute of Medical Biotechnology; Chinese Academy of Medical Science; Beijing 100050 China

3. School of Life Sciences and Biotechnology; Shanghai JiaoTong University; Shanghai 200240 China

Publisher

Wiley

Subject

Molecular Medicine,Biochemistry,Drug Discovery,Pharmacology,Organic Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cbdd.12382/fullpdf

Reference24 articles.

1. The evolution of influenza resistance and treatment;Weinstock;JAMA,2009

2. Antiviral activity of 1-adamantanamine (amantadine);Davies;Science,1964

3. Rational design of potent sialidase-based inhibitors of influenza virus replication;Itzstein;Nature,1993

4. Influenza neuraminidase inhibitors possessing a novel hydrophobic interaction in the enzyme active site: design, synthesis, and structural analysis of carbocyclic sialic acid analogues with potent anti-influenza activity;Kim;J Am Chem Soc,1997

5. Antiviral agents active against influenza A viruses;Clercq;Nat Rev Drug Discov,2006

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