An αIIbβ3antagonist prevents thrombosis without causing Fc receptor γ-chain IIa-mediated thrombocytopenia

Author:

Kuo Y.-J.1,Chen Y.-R.1,Hsu C.-C.1,Peng H.-C.1,Huang T.-F.1

Affiliation:

1. Graduate Institute of Pharmacology; College of Medicine; National Taiwan University; Taipei Taiwan

Funder

Ministry of Science and Technology, Taiwan

Publisher

Wiley

Subject

Hematology

Reference49 articles.

1. Trigramin. A low molecular weight peptide inhibiting fibrinogen interaction with platelet receptors expressed on glycoprotein IIb-IIIa complex;Huang;J Biol Chem,1987

2. Disintegrins: a family of integrin inhibitory proteins from viper venoms;Gould;Proc Soc Exp Biol Med,1990

3. Anti-thrombotic agents derived from snake venom proteins;Huang;Thromb J,2016

4. Integrin alphaIIbbeta3: from discovery to efficacious therapeutic target;Bledzka;Circ Res,2013

5. Targeting platelet receptor function in thrombus formation: the risk of bleeding;Swieringa;Blood Rev,2014

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